Background: Several studies have shown the independent association of high plasma C-reactive protein (CRP) levels with an adverse prognosis in patients with acute myocardial infarction. However, the possible association of plasma CRP levels with response to thrombolysis and short- and long-term cardiac mortality has not been investigated. The aim of this study was to evaluate these possible associations.<\/p>\n
Methods: Three hundred nineteen consecutive patients who received intravenous thrombolysis because of ST-segment elevation acute myocardial infarction were prospectively studied. Patients were classified according to tertiles of plasma CRP levels on admission.<\/p>\n
Results: Patients at the top tertile had a significantly lower incidence of complete ST-segment resolution (third vs first, P \u0001 .001, third vs second, P \u0002 .009) or Thrombolysis In Myocardial Infarction (TIMI) 3 flow in the infraction-related artery (third vs first, P \u0001 .001, third vs second, P \u0002 .02), more compromised left ventricular function (third vs first, P \u0002 .02, second vs third, P \u0002 .04), greater inhospital mortality (third vs first, P \u0002 .03, third vs second, P \u0002 .06), and greater 3-year cardiac mortality (third vs first, P \u0002 .01, third vs second, P \u0002 .07).<\/p>\n
Conclusions: Plasma levels of CRP on admission may be a predictor of reperfusion failure and of short- and longterm prognosis in patients with ST-segment elevation acute myocardial infarction. (Am Heart J 2002;144:782-9.)<\/p>\n","protected":false},"excerpt":{"rendered":"
Background: Several studies have shown the independent association of high plasma C-reactive protein (CRP) levels with an adverse prognosis in patients with acute myocardial infarction. However, the possible association of plasma CRP levels with response to thrombolysis and short- and long-term cardiac mortality has not been investigated. The aim of this study was to evaluate […]<\/p>\n","protected":false},"author":1,"featured_media":448,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"portfolio_category":[],"portfolio_skills":[],"portfolio_tags":[],"class_list":["post-447","avada_portfolio","type-avada_portfolio","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/avada_portfolio\/447","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/avada_portfolio"}],"about":[{"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/types\/avada_portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/comments?post=447"}],"version-history":[{"count":1,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/avada_portfolio\/447\/revisions"}],"predecessor-version":[{"id":449,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/avada_portfolio\/447\/revisions\/449"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/media\/448"}],"wp:attachment":[{"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/media?parent=447"}],"wp:term":[{"taxonomy":"portfolio_category","embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/portfolio_category?post=447"},{"taxonomy":"portfolio_skills","embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/portfolio_skills?post=447"},{"taxonomy":"portfolio_tags","embeddable":true,"href":"https:\/\/zairis.eu\/el\/wp-json\/wp\/v2\/portfolio_tags?post=447"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}